KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHF3
All Species:
1.52
Human Site:
T790
Identified Species:
6.67
UniProt:
Q92576
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92576
NP_055968.1
2039
229481
T790
D
T
L
E
N
Q
A
T
V
E
F
H
S
G
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106919
1983
223508
S752
D
C
V
G
L
S
L
S
Q
A
Q
Q
M
G
E
Dog
Lupus familis
XP_538985
2043
230042
K790
D
I
L
E
N
Q
A
K
V
E
V
Q
S
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505863
1253
141783
P142
P
A
A
P
A
P
K
P
S
A
D
Q
I
R
Q
Chicken
Gallus gallus
XP_426199
2065
230104
K791
S
V
L
D
T
Q
V
K
I
D
S
N
K
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780718
2329
258906
D1003
Q
S
L
K
L
R
E
D
E
R
I
S
V
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.2
87.8
N.A.
N.A.
N.A.
N.A.
45.6
60.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
22.1
Protein Similarity:
100
N.A.
94.5
92.5
N.A.
N.A.
N.A.
N.A.
51.8
72.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
38.2
P-Site Identity:
100
N.A.
13.3
66.6
N.A.
N.A.
N.A.
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
33.3
66.6
N.A.
N.A.
N.A.
N.A.
0
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
17
0
17
0
34
0
0
34
0
0
0
0
0
% A
% Cys:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
17
0
0
0
17
0
17
17
0
0
0
34
% D
% Glu:
0
0
0
34
0
0
17
0
17
34
0
0
0
34
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% F
% Gly:
0
0
0
17
0
0
0
0
0
0
0
0
0
34
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% H
% Ile:
0
17
0
0
0
0
0
0
17
0
17
0
17
17
0
% I
% Lys:
0
0
0
17
0
0
17
34
0
0
0
0
17
0
0
% K
% Leu:
0
0
67
0
34
0
17
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% M
% Asn:
0
0
0
0
34
0
0
0
0
0
0
17
0
0
0
% N
% Pro:
17
0
0
17
0
17
0
17
0
0
0
0
0
0
0
% P
% Gln:
17
0
0
0
0
50
0
0
17
0
17
50
0
0
17
% Q
% Arg:
0
0
0
0
0
17
0
0
0
17
0
0
0
17
0
% R
% Ser:
17
17
0
0
0
17
0
17
17
0
17
17
34
0
0
% S
% Thr:
0
17
0
0
17
0
0
17
0
0
0
0
0
0
0
% T
% Val:
0
17
17
0
0
0
17
0
34
0
17
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _